Publications

2024
Morgan, K. A.; Wichmann, C. W.; Osellame, L. D.; Cao, Z.; Guo, N.; Scott, A. M.; Donnelly,* P. S.
Tumor targeted alpha particle therapy with an actinium-225 labelled antibody for carbonic anhydrase IX.
Chem. Sci. 2024, 15, 3372-3381. DOI 10.1039/D3SC06365H
https://pubs.rsc.org/en/content/articlelanding/2024/sc/d3sc06365h

Rudd, S. E.; Noor, A.; Morgan, K. A.; Donnelly,* P. S.
Diagnostic Positron Emission Tomography Imaging with Zirconium-89 Desferrioxamine B Squaramide: From Bench to Bedside.
Acc. Chem. Res. 2024, 57, 1421-1433. DOI 10.1021/acs.accounts.4c00092
https://pubs.acs.org/doi/10.1021/acs.accounts.4c00092

Wasielewska, J. M.; Szostak, K.; McInnes, L. E.; Quek, H.; Chaves, J. C. S.; Liddell, J. R.; Koistinaho, J.; Oikari, L. E.; Donnelly,* P. S.; White,* A. R.
Patient-Derived Blood-Brain Barrier Model for Screening Copper Bis(thiosemicarbazone) Complexes as Potential Therapeutics in Alzheimer′s Disease.
ACS Chem. Neurosci. 2024, 15, 1432-1455.
https://pubs.acs.org/doi/10.1021/acschemneuro.3c00743

Noor,* A.; Roselt, P. D.; McGowan, E. R.; Poniger, S.; Wheatcroft, M. P.; Donnelly,* P. S.
Automated synthesis of [89Zr]ZrCl4, [89Zr]ZrDFOSquaramide-bisPh(PSMA) and [89Zr]ZrDFOSquaramide-TATE.
EJNMMI Radiopharmacy and Chemistry 2024, 9, 39. DOI 10.1186/s41181-024-00270-2
https://rdcu.be/dHnQA

Hilton, J. B. W.; Kysenius, K.; Liddell, J. R.; Mercer, S. W.; Hare, D. J.; Buncic, G.; Paul, B.; Wang, Y.; Murray, S. S.; Kilpatrick, T. J.; White, A. R.; Donnelly, P. S.; Crouch, P. J.
Evidence for decreased copper associated with demyelination in the corpus callosum of cuprizone-treated mice.
Metallomics 2024, 16. DOI 10.1093/mtomcs/mfad072
https://academic.oup.com/metallomics/article/16/1/mfad072/7511117

Hilton, J. B. W.; Kysenius, K.; Liddell, J. R.; Mercer, S. W.; Paul, B.; Beckman, J. S.; McLean, C. A.; White, A. R.; Donnelly, P. S.; Bush, A. I.; Hare, D. J.; Roberts, B. R.; Crouch, P. J.
Evidence for disrupted copper availability in human spinal cord supports CuII(atsm) as a treatment option for sporadic cases of ALS.
Scientific Reports 2024, 14, 5929. DOI 10.1038/s41598-024-55832-w
https://www.nature.com/articles/s41598-024-55832-w

Niego, B. e.; Jupp, B.; Zia, N. A.; Xu, R.; Jap, E.; Ezeani, M.; Noor, A.; Donnelly, P. S.; Hagemeyer, C. E.; Alt, K.
Molecular Imaging of Diffuse Cardiac Fibrosis with a Radiotracer That Targets Proteolyzed Collagen IV.
Radiol Cardiothorac Imaging 2024, 6, e230098. DOI 10.1148/ryct.230098
https://pubs.rsna.org/doi/10.1148/ryct.230098

Chaves, J. C. S.; Milton, L. A.; Stewart, R.; Senapati, T.; Rantanen, L. M.; Wasielewska, J. M.; Lee, S.; Hernández, D.; McInnes, L.; Quek, H.; Pébay, A.; Donnelly, P. S.; White, A. R.; Oikari, L. E.
Differential Cytokine Responses of APOE3 and APOE4 Blood–brain Barrier Cell Types to SARS-CoV-2 Spike Proteins.
J. Neuroimmune Pharmacol. 2024, 19, 22.
https://link.springer.com/article/10.1007/s11481-024-10127-9

2023
Morgan, K. A.; Rudd, S. E.; Noor, A.; Donnelly,* P. S.
Theranostic Nuclear Medicine with Gallium-68, Lutetium-177, Copper-64/67, Actinium-225, and Lead-213/203 Radionuclides.
Chem. Rev. 2023, 123, 12004-12035. DOI 10.1021/acs.chemrev.3c00456
https://pubs.acs.org/doi/abs/10.1021/acs.chemrev.3c00456

Rowan, J. A.; Rudd, S. E.; Ganio, K.; McDevitt, C. A.; White, J. M.; Donnelly,* P. S.
Copper(II) Complexes of 2,2′-Bisdipyrrins: Synthesis, Characterization, Cell Uptake, and Radiolabeling with Copper-64.
Inorg. Chem. 2023, 62, 20666-20676. DOI 10.1021/acs.inorgchem.3c01551
https://pubs.acs.org/doi/abs/10.1021/acs.inorgchem.3c01551

Donnelly, P. S.; Harrowfield, J. M.; Koutsantonis, G. A.; Lengkeek, N. A.; Ling, I.; Nealon, G. L.; McInnes, L. E.; Skelton, B. W.; Sobolev, A. N.; White, A. H.; White, J. M.
Inert Transition Metal Ion Complexes in Organic Synthesis: Protection and Activation.
Chemistry – An Asian Journal 2023, 18, e202300556. DOI 10.1002/asia.202300556
https://doi.org/10.1002/asia.202300556

Ricca, M.; Yao, S.; Le, T.; White, J. M.; Donnelly, P. S.; Rizzacasa, M. A.
A cis-β-iron(iii) SALPN catalyst for hydrogen atom transfer reductions and olefin cross couplings.
Org. Biomol. Chem. 2023, 21, 6789-6793. DOI 10.1039/D3OB01085F
https://pubs.rsc.org/en/content/articlelanding/2023/ob/d3ob01085f

Wichmann, C. W.; Poniger, S.; Guo, N.; Roselt, P.; Rudd, S. E.; Donnelly, P. S.; Blyth, B.; Van Zuylekom, J.; Rigopoulos, A.; Burvenich, I. J. G.; Morandeau, L.; Mohamed, S.; Nowak, A. K.; Hegi-Johnson, F.; MacManus, M.; Scott, A. M.
Automated radiosynthesis of [89Zr]Zr-DFOSq-Durvalumab for imaging of PD-L1 expressing tumours in vivo.
Nucl. Med. Biol. 2023, 120-121, 108351. DOI 10.1016/j.nucmedbio.2023.108351
https://doi.org/10.1016/j.nucmedbio.2023.108351

Pyun, J.; Koay, H.; Runwal, P.; Mawal, C.; Bush, A. I.; Pan, Y.; Donnelly, P. S.; Short, J. L.; Nicolazzo, J. A.
Cu(ATSM) Increases P-Glycoprotein Expression and Function at the Blood-Brain Barrier in C57BL6/J Mice.
Pharmaceutics, 2023; Vol. 15, p 2084. DOI 10.3390/pharmaceutics15082084
https://www.mdpi.com/1999-4923/15/8/2084

Hegi-Johnson, F.; Rudd, S. E.; Wichmann, C. W.; Akhurst, T.; Roselt, P.; Sursock, S.; Trinh, J.; John, T.; Devereux, L.; Donnelly, P. S.; Hicks, R. J.; Scott, A. M.; Steinfort, D.; Fox, S.; Blyth, B.; Parakh, S.; Hanna, G. G.; Callahan, J.; Burbury, K.; MacManus, M.
PD-L1 Positron Emission Tomography Imaging in Patients With Non-Small Cell Lung Cancer: Preliminary Results of the ImmunoPET Phase 0 Study.
Int. J. Radiat. Oncol. Biol. Phys. 2023. DOI 10.1016/j.ijrobp.2023.05.019
https://doi.org/10.1016/j.ijrobp.2023.05.019

Nikseresht, S.; Hilton, J. B. W.; Liddell, J. R.; Kysenius, K.; Bush, A. I.; Ayton, S.; Koay, H.; Donnelly, P. S.; Crouch, P. J. Transdermal Application of Soluble CuII(atsm) Increases Brain and Spinal Cord Uptake Compared to Gavage with an Insoluble Suspension.
Neuroscience 2023, 509, 125-131. DOI 10.1016/j.neuroscience.2022.11.026
https://doi.org/10.1016/j.neuroscience.2022.11.026

2022
Paterson, B. M.; White, J. M.; Donnelly,* P. S.
An icosanuclear silver(I) cluster supported by bis(thiosemicarbazonato) ligands.
Aust. J. Chem., 2022, 75, 631-635. DOI 10.1071/CH21335 (invited contribution Glen Deacon Special Issue)
https://www.publish.csiro.au/ch/CH21335

Choo, X. Y.; McInnes, L. E.; Grubman, A.; Wasielewska, J. M.; Belaya, I.; Burrows, E.; Quek, H.; Martín, J. C.; Loppi, S.; Sorvari, A.; Rait, D.; Powell, A.; Duncan, C.; Liddell, J. R.; Tanila, H.; Polo, J. M.; Malm, T.; Kanninen, K. M.; Donnelly,* P. S.; White,* A. R.
Novel Anti-Neuroinflammatory Properties of a Thiosemicarbazone-Pyridylhydrazone Copper(II) Complex.
Int. J. Mol. Sci., 2022, 23. 10722. DOI 10.3390/ijms231810722
https://www.mdpi.com/1422-0067/23/18/10722

Kelderman, C. A. A.; Davey, P. R. W. J.; Ma, M. T.; de Veer, M.; Salimova, E.; Donnelly, P. S.; Paterson, B. M.
Hexadentate technetium-99m bis(thiosemicarbazonato) complexes: synthesis, characterization and biodistribution.
Dalton Trans. 2022, 51, 14064-14078. DOI 10.1039/d2dt01264b
https://pubs.rsc.org/en/content/articlelanding/2022/dt/d2dt01264b

Yang, Y.; Spyrou, B.; White, J. M.; Canty, A. J.; Donnelly, P. S.; O’Hair, R. A. J.
Palladium-Mediated CO2 Extrusion Followed by Insertion of Allenes: Translating Mechanistic Studies to Develop a One-Pot Method for the Synthesis of Alkenes.
Organometallics 2022, 41, 1595-1608. DOI 10.1021/acs.organomet.2c00005
https://pubs.acs.org/doi/abs/10.1021/acs.organomet.2c00005

Yang, Y.; Spyrou, B.; Donnelly, P. S.; Canty, A. J. O’Hair, R. A. J.
The role of silver carbonate as a catalyst in the synthesis of N-phenylbenzamide from benzoic acid and phenyl isocyanate: a mechanistic exploration. (invited contribution Glen Deacon Special Issue)
Aust. J. Chem., 2022, 75, 495-505. DOI 10.1071/CH21258
https://www.publish.csiro.au/ch/CH21258

Ricca, M.; Zhang, W.; Li J; Fellowes, T.; White, J. M.; Donnelly, P. S.; Rizzacasa, M. A.
Synthesis of acyloin natural products by Mukaiyama hydration.
Org. Biomol. Chem. 2022, 20, 4038-4047. DOI: 10.1039/d2ob00651k
https://pubs.rsc.org/en/content/articlelanding/2022/ob/d2ob00651k

Pyun, J.; McInnes, L. E.; Donnelly, P. S.; Mawal, C.; Bush, A. I.; Short, J. L.; Nicolazzo, J. A.
Copper bis(thiosemicarbazone) complexes modulate P-glycoprotein expression and function in human brain microvascular endothelial cells.
J. Neurochem. 2022, 162, 226-244. DOI: 10.1111/jnc.15609
https://onlinelibrary.wiley.com/doi/full/10.1111/jnc.15609

Hegi-Johnson, F.; Rudd, S.; Hicks, R. J.; De Ruysscher, D.; Trapani, J. A.; John, T.; Donnelly, P.; Blyth, B.; Hanna, G.; Everitt, S.; Roselt, P.; MacManus, M. P.
Imaging immunity in patients with cancer using positron emission tomography.
npj Precis. Oncol. 2022, 6, 24. DOI 10.1038/s41698-022-00263-x
https://www.nature.com/articles/s41698-022-00263-x

Ezeani, M.; Noor, A.; Donnelly, P. S.; Niego, B.;  Hagemeyer, C. E.
Assessment of the epi-pericardial fibrotic substrate by collagen-targeted probes.
Sci. Rep., 2022, 2, 5702. DOI 10.1038/s41598-022-08688-x
https://www.nature.com/articles/s41598-022-08688-x

Hegi-Johnson, F.; Rudd, S. E.; Wichmann, C.; Akhurst, T.; Roselt, P.; Trinh, J.; John, T.; Devereux, L.; Donnelly, P. S.; Hicks, R.; Scott, A. M.; Steinfort, D.; Fox, S.; Blyth, B.; Parakh, S.; Hanna, G. G.; Callahan, J.; Burbury, K.; MacManus, M. ImmunoPET: IMaging of cancer imMUNOtherapy targets with positron Emission Tomography: a phase 0/1 study characterising PD-L1 with 89Zr-durvalumab (MEDI4736) PET/CT in stage III NSCLC patients receiving chemoradiation study protocol.
BMJ Open, 2022, 12, e056708.
https://bmjopen.bmj.com/content/12/11/e056708

2021
Rudd, S. E.; Van Zuylekom, J. K.; Raicevic, A.; Pearce, L. A.; Cullinane, C.; Williams, C. C.; Adams, T. E.; Hicks, R. J.; Donnelly,* P. S.
Enzyme mediated incorporation of zirconium-89 or copper-64 into a fragment antibody for same day imaging of epidermal growth factor receptor.
Chem. Sci., 2021, 12, 9004-9016. DOI 10.1039/D1SC01422F (Journal Pick of the Week)
https://pubs.rsc.org/en/content/articlelanding/2021/sc/d1sc01422f#!divAb

McInnes, L. E.; Cullinane, C.; Roselt, P. D.; Jackson, S.; Blyth, B. J.; van Dam, E. M.; Zia, N. A.; Harris, M. J.; Hicks, R. J.; Donnelly,* P. S.
Therapeutic efficacy of a bivalent inhibitor of prostate-specific membrane antigen labeled with 67Cu.
J. Nucl. Med. 2021, 62, 829. DOI 10.2967/jnumed.120.251579
https://jnm.snmjournals.org/content/62/6/829

Spyrou, B.; Hungnes, I. N.; Mota, F.; Bordoloi, J.; Blower, P. J.; White, J. M.; Ma, M. T.; Donnelly*, P. S.
Oxorhenium(v) and oxotechnetium(v) complexes of N3S tetradentate ligands with a styrylpyridyl functional group: Toward imaging agents to assist in the diagnosis of alzheimer’s disease.
Inorg. Chem. 2021, 60, 13669-13680. DOI 10.1021/acs.inorgchem.1c01992
https://pubs.acs.org/doi/10.1021/acs.inorgchem.1c01992

Noor, A.; Van Zuylekom, J. K.; Rudd, S. E.; Waldeck, K.; Roselt, P. D.; Haskali, M. B.; Wheatcroft, M. P.; Yan, E.; Hicks, R. J.; Cullinane, C.; Donnelly,* P. S.
Imaging somatostatin positive tumors with tyr3‐octreotate/octreotide conjugated to desferrioxamine b squaramide radiolabeled with either zirconium-89 or gallium-68.
Bioconjugate Chem. 2021, 32, 1192-1203. DOI: 10.1021/acs.bioconjchem.1c00109
https://pubs.acs.org/doi/10.1021/acs.bioconjchem.1c00109

Morgan, K. A.; Donnelly*, P. S.
Metallic radionuclides for diagnostic imaging and cancer radiotherapy: The development of theragnostic matched pairs and targeted alpha therapy.
In Adv. Inorg. Chem., Hubbard, C. D.; van Eldik, R., Eds. Academic Press: 2021; 78, p 37-63.
https://www.sciencedirect.com/science/article/pii/S089888382100026X

McMahon, J. H.; Zerbato, J. M.; Lau, J. S. Y.; Lange, J. L.; Roche, M.; Tumpach, C.; Dantanarayana, A.; Rhodes, A.; Chang, J.; Rasmussen, T. A.; Mackenzie, C. A.; Alt, K.; Hagenauer, M.; Roney, J.; O’Bryan, J.; Carey, A.; McIntyre, R.; Beech, P.; O’Keefe, G. J.; Wichmann, C. W.; Scott, F. E.; Guo, N.; Lee, S.-T.; Liu, Z.; Caskey, M.; Nussenzweig, M. C.; Donnelly, P. S.; Egan, G.; Hagemeyer, C. E.; Scott, A. M.; Lewin, S. R.
A clinical trial of non-invasive imaging with an anti-hiv antibody labelled with copper-64 in people living with hiv and uninfected controls.
EBioMedicine 2021, 65, 103252. DOI: 10.1016/j.ebiom.2021.103252
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(21)00045-1/fulltext

Liapis, V.; Tieu, W.; Wittwer, N. L.; Gargett, T.; Evdokiou, A.; Takhar, P.; Rudd, S. E.; Donnelly, P. S.; Brown, M. P.; Staudacher, A. H.
Positron Emission Tomographic Imaging of Tumor Cell Death Using Zirconium-89-Labeled APOMAB® Following Cisplatin Chemotherapy in Lung and Ovarian Cancer Xenograft Models.
Mol. Imag. Biol. 2021, 23, 914-928
https://link.springer.com/article/10.1007%2Fs11307-021-01620-1

Ezeani, M.; Hagemeyer Christoph, E.; Niego, B. e.; Noor, A.; Donnelly Paul, S.; Alt, K.; Lal, S.
Collagen-targeted peptides for molecular imaging of diffuse cardiac fibrosis.
J. Amer. Heart Assoc. 2021, e022139. DOI 10.1161/JAHA.121.022139
https://www.ahajournals.org/doi/10.1161/JAHA.121.022139

Lum, J. S.; Brown, M. L.; Farrawell, N. E.; McAlary, L.; Ly, D.; Chisholm, C. G.; Snow, J.; Vine, K. L.; Karl, T.; Kreilaus, F.; McInnes, L. E.; Nikseresht, S.; Donnelly, P. S.; Crouch, P. J.; Yerbury, J. J.
CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1G93A mice with a C57BL/6 background.
Sci. Rep. 2021, 11, 19392
https://www.nature.com/articles/s41598-021-98317-w

Altalhi, W. A. O.; McKay, A. I.; Spyrou, B.; Canty, A. J.; Donnelly, P. S.; O’Hair, R. A. J.
Examination of n,n-dimethylbenzylamine as a substrate for ruthenium-catalysed c-h (thio)amidation: A mass spectrometry and dft directed study.
J. Organomet. Chem. 2021, 950, 121973. DOI 10.1016/j.jorganchem.2021.121973
https://www.sciencedirect.com/science/article/pii/S0022328X21002941

Olia, M. B. A.; Donnelly, P.S.;  Hollenberg,  L. C. L.; Mulvaney, P; Simpson; D. A.
Advances in the Surface Functionalization of Nanodiamonds for Biological Applications: A Review
ACS Appl. Nano Mater. 2021, 4, 9985-10005.
https://pubs.acs.org/doi/abs/10.1021/acsanm.1c02698

2020
Cullinane, C.; Hicks Rodney, J.; Jeffery Charmaine, M.; van Dam Ellen, M.; Harris Matthew, J.; Roselt Peter, D.; Jackson, P.; Binns, D.; Jackson, S.; van Zuylekom, J.; Kuan, K.; Donnelly* Paul, S.
Peptide Receptor Radionuclide Therapy with 67Cu-CuSarTATE is Highly Efficacious Against a Somatostatin Positive Neuroendocrine Tumor Model.
J. Nucl. Med., 2020, 61, 1800-1805. DOI: 10.2967/jnumed.120.243543
https://jnm.snmjournals.org/content/early/2020/05/14/jnumed.120.243543

Noor, A.; Van Zuylekom, J. K.; Rudd, S. E.; Waldeck, K.; Roselt, P. D.; Haskali, M. B.; Wheatcroft, M. P.; Yan, E.; Hicks, R. J.; Cullinane, C.; Donnelly*, P. S. 
Bivalent Inhibitors of Prostate-Specific Membrane Antigen Conjugated to Desferrioxamine B Squaramide Labeled with Zirconium-89 or Gallium-68 for Diagnostic Imaging of Prostate Cancer.
J. Med. Chem. 2020, 63, 9258-9270. DOI 10.1021/acs.jmedchem.0c00291
10.1021/acs.jmedchem.0c00291

Keinanen, O.; Fung, K.; Brennan, J. M.; Zia, N.; Harris, M.; van Dam, E.; Biggin, C.; Hedt, A.; Stoner, J.; Donnelly, P. S.; Lewis, J. S.; Zeglis, B. M.
Harnessing 64cu/67cu for a theranostic approach to pretargeted radioimmunotherapy.
Proc. Natl. Acad. Sci. U. S. A. 2020, 117, 28316-28327. DOI 10.1073/pnas.2009960117
https://www.pnas.org/content/117/45/28316.short

Kelly, J. M.; Ponnala, S.; Amor-Coarasa, A.; Zia, N. A.; Nikolopoulou, A.; Williams, C.; Schlyer, D. J.; DiMagno, S. G.; Donnelly, P. S.; Babich, J. W.
Preclinical evaluation of a high-affinity sarcophagine-containing PSMA ligand for 64Cu/67Cu-based theranostics in prostate cancer.
Mol. Pharmaceutics 2020, 17, 1954-1962. DOI: 10.1021/acs.molpharmaceut.0c00060
https://pubs.acs.org/doi/abs/10.1021/acs.molpharmaceut.0c00060

Liapis, V.; Wittwer Nicole, L.; Brown Michael, P.; Staudacher Alexander, H.; Tieu, W.; Brown Michael, P.; Staudacher Alexander, H.; Tieu, W.; Rudd Stacey, E.; Donnelly Paul, S.; Brown Michael, P.
Improved non-invasive positron emission tomographic imaging of chemotherapy-induced tumor cell death using zirconium-89-labeled apomab®.
Eur. J. Nucl. Med. Mol. Imaging: Radiopharmacy and Chemistry 2020, 5, 27. DOI 10.1186/s41181-020-00109-6
https://ejnmmipharmchem.springeropen.com/articles/10.1186/s41181-020-00109-6

Southon, A.; Szostak, K.; Acevedo, K. M.; Dent, K. A.; Volitakis, I.; Belaidi, A. A.; Barnham, K. J.; Crouch, P. J.; Ayton, S.; Donnelly, P. S.; Bush, A. I.
CuII(atsm) inhibits ferroptosis: Implications for treatment of neurodegenerative disease.
Br. J. Pharmacol. 2020, 177, 656-667. DOI: 10.1111/bph.14881
https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bph.14881

Noor, A.; Hayne, D. J.; Lim, S.; Van Zuylekom, J. K.; Cullinane, C.; Roselt, P. D.; McLean, C. A.; White, J. M.; Donnelly*, P. S.
Copper Bis(thiosemicarbazonato)-stilbenyl Complexes That Bind to Amyloid-β Plaques.
Inorg. Chem. 2020, 59, 11658-11669. DOI: 10.1021/acs.inorgchem.0c01520
https://pubs.acs.org/doi/abs/10.1021/acs.inorgchem.0c01520

Koay, H.; Haskali, M. B.; Roselt, P. D.; White, J. M.; Donnelly*, P. S.
Gallium Fluoride Complexes with Acyclic Bispicolinic Ligands as Potential New Fluorine-18 Labelled Imaging Agents.
Eur. J. Inorg. Chem. 2020, 3378-3386. DOI: 10.1002/ejic.202000547
https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/ejic.202000547

Wiratpruk, N.; Noor, A.; McLean, C. A.; Donnelly, P. S.; Barnard, P. J. Charge neutral rhenium tricarbonyl complexes of tridentate N-heterocyclic carbene ligands that bind to amyloid plaques of Alzheimer’s disease.
Dalton Trans. 2020, 49, 4559-4569. DOI: 10.1039/c9dt04687a
https://pubs.rsc.org/en/content/articlelanding/2020/dt/c9dt04687a#!divAbstract

Yang, Y.; Canty, A. J.; McKay, A. I.; Donnelly, P. S.; O’Hair, R. A. J. Palladium-Mediated CO2 Extrusion Followed by Insertion of Isocyanates for the Synthesis of Benzamides: Translating Fundamental Mechanistic Studies To Develop a Catalytic Protocol.
Organometallics 2020, 39, 453-467. DOI: 10.1021/acs.organomet.9b00820
https://pubs.acs.org/doi/10.1021/acs.organomet.9b00820

McKay, A. I.; Altalhi, W. A. O.; McInnes, L. E.; Czyz, M. L.; Canty, A. J.; Donnelly*, P. S.; O’Hair*, R. A. J. Identification of the Side Products That Diminish the Yields of the Monoamidated Product in Metal-Catalyzed C-H Amidation of 2-Phenylpyridine with Arylisocyanates.
J. Org. Chem. 2020, 85, 2680-2687. DOI: 10.1021/acs.joc.9b02831
https://pubs.acs.org/doi/10.1021/acs.joc.9b02831

2019
Zia, N. A.; Cullinane, C.; Van Zuylekom, J. K.; Waldeck, K.; McInnes, L. E.; Buncic, G.; Haskali, M. B.; Roselt, P. D.; Hicks, R. J.; Donnelly*, P. S.
A Bivalent Inhibitor of Prostate Specific Membrane Antigen Radiolabeled with Copper-64 with High Tumor Uptake and Retention
Angew. Chem., Int. Ed. 2019, 58, 14991-14994. DOI: 10.1002/anie.201908964
https://onlinelibrary.wiley.com/doi/10.1002/anie.201908964

Hicks, R. J.; Jackson, P.; Kong, G.; Ware, R. E.; Hofman, M. S.; Pattison, D. A.; Akhurst, T. A.; Drummond, E.; Roselt, P.; Callahan, J.; Price, R.; Jeffery, C. M.; Hong, E.; Noonan, W.; Herschtal, A.; Hicks, L. J.; Hedt, A.; Harris, M.; Paterson, B. M.; Donnelly, P. S.
64Cu-SARTATE PET Imaging of Patients with Neuroendocrine Tumors Demonstrates High Tumor Uptake and Retention, Potentially Allowing Prospective Dosimetry for Peptide Receptor Radionuclide Therapy.
J. Nucl. Med., 2019, 60, 777-785. DOI: 10.2967/jnumed.118.217745
http://jnm.snmjournals.org/content/60/6/777.abstract

Donnelly*, P. S.; North, A. J.; Radjah, N. C.; Ricca, M.; Robertson, A.; White, J. M.; Rizzacasa, M. A.
An effective cis-β-octahedral Mn(III) SALPN catalyst for the Mukaiyama-Isayama hydration of α,β-unsaturated esters.
Chem. Commun., 2019, 55, 7699-7702. DOI: 10.1039/c9cc03921j
https://pubs.rsc.org/en/content/articlelanding/2019/cc/c9cc03921j

Chen, L.; Hayne, D. J.; Doeven, E. H.; Agugiaro, J.; Wilson, D. J. D.; Henderson, L. C.; Connell, T. U.; Nai, Y. H.; Alexander, R.; Carrara, S.; Hogan, C. F.; Donnelly, P. S.; Francis, P. S.A conceptual framework for the development of iridium(III) complex-based electrogenerated chemiluminescence labels.
Chem. Sci. 2019, 10, 8654-8667. DOI:10.1039/C9SC01391A
https://pubs.rsc.org/en/content/articlelanding/2019/sc/c9sc01391a#!divAbstract

Paterson, B. M.; Cullinane, C.; Crouch, P. J.; White, A. R.; Barnham, K. J.; Roselt, P. D.; Noonan, W.; Binns, D.; Hicks, R. J.; Donnelly*, P. S.
Modification of Biodistribution and Brain Uptake of Copper Bis(thiosemicarbazonato) Complexes by the Incorporation of Amine and Polyamine Functional Groups.
Inorg. Chem. 2019, 58, 4540 – 4552, DOI: 10.1021/acs.inorgchem.9b00117
https://pubs.acs.org/doi/10.1021/acs.inorgchem.9b00117

McInnes, L. E.; Noor, A.; Kysenius, K.; Cullinane, C.; Roselt, P.; McLean, C. A.; Chiu, F. C. K.; Powell, A. K.; Crouch, P. J.; White, J. M.; Donnelly*, P. S.
Potential Diagnostic Imaging of Alzheimer’s Disease with Copper-64 Complexes That Bind to Amyloid-β Plaques.
Inorg. Chem. 2019, 58, 3382-3395. DOI: 10.1021/acs.inorgchem.8b03466
https://pubs.acs.org/doi/10.1021/acs.inorgchem.8b03466

Yang, Y.; Noor, A.; Canty, A. J.; Ariafard, A.; Donnelly*, P. S.; O’Hair*, R. A. J.
Synthesis of Amidines by Palladium-Mediated CO2 Extrusion Followed by Insertion of Carbodiimides: Translating Mechanistic Studies to Develop a One-Pot Method.
Organometallics 2019, 38, 424-435. DOI: 10.1021/acs.organomet.8b00776
https://pubs.acs.org/doi/10.1021/acs.organomet.8b00776

Wang, Z.; Yang, Y.; Donnelly, P. S.; Canty, A. J.; O’Hair, R. A. J.
Desulfination versus decarboxylation as a means of generating three- and five-coordinate organopalladium complexes [(phen)nPd(C6H5)]+ (n = 1 and 2) to study their fundamental bimolecular reactivity
J. Organomet. Chem. 2019, 882, 42-49. DOI: 10.1016/j.jorganchem.2018.11.028
https://doi.org/10.1016/j.jorganchem.2018.11.028

McInnes, L. E.; Noor, A.; Roselt, P. D.; McLean, C. A.; White, J. M.; Donnelly*, P. S.
A Copper Complex of a Thiosemicarbazone-Pyridylhydrazone Ligand Containing a Vinylpyridine Functional Group as a Potential Imaging Agent for Amyloid-β Plaques
Aust. J. Chem. 2019, 72, 827-834. DOI: 10.1071/ch19311
http://www.publish.csiro.au/CH/CH19311

Alcantara, S.; Dai, Q.; Howard, C. B.; Mahler, S. M.; Wheatley, A. K.; De Rose, R.; Brannon, P. T.; Paterson, B. M.; Donnelly, P. S.; Thurecht, K. J.; Caruso, F.; Kent, S. J.
Modulating Targeting of Poly(ethylene glycol) Particles to Tumor Cells Using Bispecific Antibodies.
Adv. Healthcare Mater. 2019, 8, DOI: 10.1002/adhm.201801607
https://onlinelibrary.wiley.com/doi/10.1002/adhm.201801607

Pearce, H. A.; Qian, H.; Connell, T. U.; Huang, D.; Gottstein, C.; Donnelly, P. S.; Peter, K.; Gregorevic, P.; Hagemeyer, C. E. Site-Specific Glycation and Chemo-enzymatic Antibody Sortagging for the Retargeting of rAAV6 to Inflamed Endothelium.
Mol. Ther.–Methods Clin. Dev. 2019, 14, 261-269. DOI: 10.1016/j.omtm.2019.07.003
https://www.sciencedirect.com/science/article/pii/S2329050119300750

2018
Acevedo, K. M.; Hayne, D. J.; McInnes, L. E.; Noor, A.; Duncan, C.; Moujalled, D.; Volitakis, I.; Rigopoulos, A.; Barnham, K. J.; Villemagne, V. L.; White, A. R.; Donnelly*, P. S.
Effect of Structural Modifications to Glyoxal-bis(thiosemicarbazonato)copper(II) Complexes on Cellular Copper Uptake, Copper-Mediated ATP7A Trafficking, and P-Glycoprotein Mediated Efflux.
J. Med. Chem. 2018, 61, 711-723. DOI: 10.1021/acs.jmedchem.7b01158
https://protect-au.mimecast.com/s/wwBGCL7rxDsEEOVyuBbd2Z?domain=pubs.acs.org

Fletcher, S. P.; Noor, A.; Hickey, J. L.; McLean, C. A.; White, J. M.; Donnelly*, P. S.
Rhenium and technetium complexes of thioamide derivatives of pyridylhydrazine that bind to amyloid-β plaques.
J. Biol. Inorg. Chem. 2018, 23, 1139-1151. DOI: 10.1007/s00775-018-1590-4
https://link.springer.com/article/10.1007/s00775-018-1590-4

Connell, T. U.; Donnelly*, P. S.
Labelling proteins and peptides with phosphorescent d6 transition metal complexes.
Coord. Chem. Rev. 2018, 375, 267-284. DOI: 10.1016/j.ccr.2017.12.001
https://www.sciencedirect.com/science/article/abs/pii/S0010854517305702

Soulsby, L. C.; Hayne, D. J.; Doeven, E. H.; Wilson, D. J. D.; Agugiaro, J.; Connell, T. U.; Chen, L.; Hogan, C. F.; Kerr, E.; Adcock, J. L.; Donnelly, P. S.; White, J. M.; Francis, P. S.
Mixed annihilation electrogenerated chemiluminescence of iridium(III) complexes.
Phys. Chem. Chem. Phys. 2018, 20, 18995-19006. DOI: 10.1039/c8cp01737a
https://pubs.rsc.org/en/content/articlelanding/2018/cp/c8cp01737a#!divAbstract

Choo, X. Y.; Liddell, J. R.; Huuskonen, M. T.; Grubman, A.; Moujalled, D.; Roberts, J.; Kysenius, K.; Patten, L.; Quek, H.; Oikari, L. E.; Duncan, C.; James, S. A.; McInnes, L. E.; Hayne, D. J.; Donnelly, P. S.; Pollari, E.; Vähätalo, S.; Lejavová, K.; Kettunen, M. I.; Malm, T.; Koistinaho, J.; White, A. R.; Kanninen, K. M.
CuII(atsm) Attenuates Neuroinflammation.
Frontiers in Neuroscience 2018, 12. DOI: 10.3389/fnins.2018.00668
https://www.frontiersin.org/articles/10.3389/fnins.2018.00668/full

Keenan, R. J.; Chan, J.; Donnelly, P. S.; Barnham, K. J.; Jacobson, L. H. The social defeat/overcrowding murine psychosocial stress model results in a pharmacologically reversible body weight gain but not depression – related behaviours.
Neurobiology of Stress 2018, 9, 176-187. DOI: 10.1016/j.ynstr.2018.09.008
https://www.sciencedirect.com/science/article/pii/S235228951830064X

McKenzie-Nickson, S.; Chan, J.; Perez, K.; Hung, L. W.; Cheng, L.; Sedjahtera, A.; Gunawan, L.; Adlard, P. A.; Hayne, D. J.; McInnes, L. E.; Donnelly, P. S.; Finkelstein, D. I.; Hill, A. F.; Barnham, K. J. Modulating Protein Phosphatase 2A Rescues Disease Phenotype in Neurodegenerative Tauopathies.
ACS Chem. Neurosci. 2018, 9, 2731-2740. DOI: 10.1021/acschemneuro.8b00161
https://pubs.acs.org/doi/10.1021/acschemneuro.8b00161

2017
Paterson, B. M.; White, K. F.; White, J. M.; Abrahams, B. F.; Donnelly*, P. S.
Guest-induced Assembly of Bis(thiosemicarbazonato) Zinc(II) Coordination Nanotubes.
Angew. Chem., Int. Ed. 2017, 56, 8370-8374. DOI 10.1002/anie.201701596
http://onlinelibrary.wiley.com/doi/10.1002/anie.201701596/abstract 

Karas, J. A.; Noor, A.; Schieber, C.; Connell, T. U.; Separovic, F.; Donnelly*, P. S.
The efficient synthesis and purification of amyloid-β(1-42) using an oligoethylene glycol-containing photocleavable lysine tag.
Chem. Commun. 2017, 53, 6903-6905. DOI: 10.1039/c7cc03147e
http://pubs.rsc.org/en/content/articlelanding/2017/cc/c7cc03147e#!divAbstract

Noor, A.; Li, J.; Khairallah, G. N.; Li, Z.; Ghari, H.; Canty, A. J.; Ariafard, A.; Donnelly*, P. S.; O’Hair, R. A. J. A one-pot route to thioamides discovered by gas-phase studies: palladium-mediated CO2 extrusion followed by insertion of isothiocyanates.
Chem. Commun. 2017, 53, 3854-3857. DOI: 10.1039/c7cc00865a
http://pubs.rsc.org/en/Content/ArticleLanding/2017/CC/c7cc00865a#!divAbstract

Chan, C. Y.; Noor, A.; McLean, C. A.; Donnelly, P. S.; Barnard, P. J.
Rhenium(I) complexes of N-heterocyclic carbene ligands that bind to amyloid plaques of Alzheimer’s disease
Chem. Commun., 2017. 2017, 53, 2311-2314. DOI: 10.1039/C6CC10066J
http://pubs.rsc.org/en/content/articlelanding/2017/cc/c6cc10066j#!divAbstract

McInnes, L. E.; Rudd, S. E.; Donnelly*, P. S.
Copper, gallium and zirconium positron emission tomography imaging agents: The importance of metal ion speciation.
Coord. Chem. Rev. 2017, 352, 499-516. DOI 10.1016/j.ccr.2017.05.011
https://www.sciencedirect.com/science/article/pii/S0010854516303228

North, A. J.; Karas, J. A.; Ma, M. T.; Blower, P. J.; Ackermann, U.; White, J. M.; Donnelly, P. S.
Rhenium and Technetium-oxo Complexes with Thioamide Derivatives of Pyridylhydrazine Bifunctional Chelators Conjugated to the Tumour Targeting Peptides Octreotate and Cyclic-RGDfK.
Inorg. Chem. 2017, 56, 9725-9741. DOI 10.1021/acs.inorgchem.7b01247
http://pubs.acs.org/doi/abs/10.1021/acs.inorgchem.7b01247

Simpson, D. A.; Ryan, R. G.; Hall, L. T.; Panchenko, E.; Drew, S. C.; Petrou, S.; Donnelly, P. S.; Mulvaney, P.; Hollenberg, L. C. L.
Electron paramagnetic resonance microscopy using spins in diamond under ambient conditions.
Nature Commun., 2017, 8, 458. DOI 10.1038/s41467-017-00466-y
https://www.nature.com/articles/s41467-017-00466-y

Abrahams, B. F.; Dharma, A. D.; Donnelly, P. S.; Hudson, T. A.; Kepert, C. J.; Robson, R.; Southon, P. D.; White, K. F.
Tunable Porous Coordination Polymers for the Capture, Recovery and Storage of Inhalation Anesthetics.
Chem. Eur. J. 2017, 23, 7871-7875. DOI: 10.1002/chem.201700389
http://onlinelibrary.wiley.com/doi/10.1002/chem.201700389/abstract

Hilton, J. B.; Mercer, S. W.; Lim, N. K. H.; Faux, N. G.; Buncic, G.; Beckman, J. S.; Roberts, B. R.; Donnelly, P. S.; White, A. R.; Crouch, P. J.
CuII(atsm) improves the neurological phenotype and survival of SOD1G93A mice and selectively increases enzymatically active SOD1 in the spinal cord.
Sci. Rep. 2017, 7, 42292. DOI 10.1038/srep42292
https://www.nature.com/articles/srep42292

Yap, M. L.; McFadyen, J. D.; Wang, X.; Zia, N. A.; Hohmann, J. D.; Ziegler, M.; Yao, Y.; Pham, A.; Harris, M.; Donnelly, P. S.; Hogarth, P. M.; Pietersz, G. A.; Lim, B.; Peter, K. Targeting Activated Platelets: A Unique and Potentially Universal Approach for Cancer Imaging.
Theranostics 2017, 7, 2565-2574. DOI: 10.7150/thno.19900
http://www.thno.org/v07p2565.pdf

Huuskonen, M. T.; Tuo, Q.-z.; Loppi, S.; Dhungana, H.; Korhonen, P.; McInnes, L. E.; Donnelly, P. S.; Grubman, A.; Wojciechowski, S.; Lejavova, K.; Pomeshchik, Y.; Periviita, L.; Kosonen, L.; Giordano, M.; Walker, F. R.; Liu, R.; Bush, A. I.; Koistinaho, J.; Malm, T.; White, A. R.; Lei, P.; Kanninen, K. M.
The Copper bis(thiosemicarbazone) Complex CuII(atsm) Is Protective Against Cerebral Ischemia Through Modulation of the Inflammatory Milieu.
Neurotherapeutics 2017, 14, 519-532. DOI: 10.1007/s13311-016-0504-9
https://link.springer.com/article/10.1007%2Fs13311-016-0504-9

Daly, S.; Choi, C. M.; Zavras, A.; Krstic, M.; Chirot, F.; Connell, T. U.; Williams, S. J.; Donnelly, P. S.; Antoine, R.; Giuliani, A.; Bonacic-Koutecky, V.; Dugourd, P.; O’Hair, R. A. J.
Gas-Phase Structural and Optical Properties of Homo- and Heterobimetallic Rhombic Dodecahedral Nanoclusters [Ag14-nCun(C≡CtBu)12X]+ (X = Cl and Br): Ion Mobility, VUV and UV Spectroscopy, and DFT Calculations.
J. Phys. Chem. C 2017, 121, 10719-10727. DOI: 10.1021/acs.jpcc.7b02663
http://pubs.acs.org/doi/abs/10.1021/acs.jpcc.7b02663

2016
Rudd,S. E., Roselt, P., Cullinane C. C., Hicks, R. J.  and Donnelly* P. S.
A desferrioxamine B squaramide ester for the incorporation of zirconium-89 into antibodies
Chem. Commun., 2016, 52, 11889-11892. DOI: 10.1039/C6CC05961A
http://xlink.rsc.org/?DOI=C6CC05961A

Hayne, D. J.; White, J. M.; McLean, C. A.; Villemagne, V. L.; Barnham, K. J.; Donnelly*, P. S.
Synthesis of Oxorhenium(V) and Oxotechnetium(V) Complexes That Bind to Amyloid-β Plaques.
Inorg. Chem. 2016, 55, 7944−7953. DOI: 10.1021/acs.inorgchem.6b00972
http://pubsdc3.acs.org/articlesonrequest/AOR-QKE47ddMGwgkFCazaS7j

Connell, T. U., White, J. M., Smith, T. A. and Donnelly*, P. S.
Luminescent Iridium(III) Cyclometalated Complexes with 1,2,3-Triazole “Click” Ligands
Inorg. Chem. 2016 55, 2776. DOI: 10.1021/acs.inorgchem.5b02607
http://pubsdc3.acs.org/articlesonrequest/AOR-M7xdFSibQrqJjXkT3sI7

Li, J., White, J. M., Mulder, R. J., Reid, G. E., Donnelly, P. S., O’Hair, R. A. J.
Synthesis, Structural Characterization, and Gas-Phase Unimolecular Reactivity of Bis(diphenylphosphino)amino Copper Hydride Nanoclusters [Cu3(X)(μ3-H)((PPh2)2NH)3](BF4), Where X = μ2-Cl and μ3-BH4
Inorg. Chem. 2016 55, 9858−9868. DOI: 10.1021/acs.inorgchem.6b01696
http://pubs.acs.org/doi/abs/10.1021/acs.inorgchem.6b01696

Lange, J. L.; Hayne, D. J.; Roselt, P.; McLean, C. A.; White, J. M.; Donnelly*, P. S.
A gallium(III) Schiff base-curcumin complex that binds to amyloid-β plaques.
J. Inorg. Biochem. 2016, 162, 274–279. DOI: 10.1016/j.jinorgbio.2016.02.029
http://www.sciencedirect.com/science/article/pii/S0162013416300563
https://authors.elsevier.com/a/1T~KQarcm8A0J

Kerr, E.; Doeven, E. H.; Barbante, G. J.; Hogan, C. F.; Hayne, D. J.; Donnelly, P. S.; Francis, P. S.
New perspectives on the annihilation electrogenerated chemiluminescence of mixed metal complexes in solution.
Chem. Sci. 2016, 7, 5271-5279. DOI: 10.1039/c6sc01570k
http://pubs.rsc.org/en/content/articlepdf/2016/sc/c6sc01570k

Loits, D.; Braese, S.; North, A. J.; White, J. M.; Donnelly, P. S.; Rizzacasa, M. A.
Synthesis of Homochiral CoIII- and MnIV-[2.2]Paracyclophane Schiff Base Complexes with Predetermined Chirality at the Metal Centre.
Eur. J. Inorg. Chem. 2016, 3541-3544. DOI: 10.1002/ejic.201600750
http://onlinelibrary.wiley.com/doi/10.1002/ejic.201600750/abstract

Smith, Z. M., Kerr, E., Doeven, E. H., Connell, T. U., Barnett, N. W., Donnelly, P. S., Haswell, S. J. and Francis, P. S.
Analytically useful blue chemiluminescence from a water-soluble iridium(III) complex containing a tetraethylene glycol functionalised triazolylpyridine ligand
Analyst 2016 141 2140. DOI: 10.1039/c6an00141f
http://pubs.rsc.org/en/Content/ArticleLanding/2016/AN/c6an00141f#!divAbstract

Ziegler, M.; Alt, K.; Paterson, B. M.; Kanellakis, P.; Bobik, A.; Donnelly, P. S.; Hagemeyer, C. E.; Peter, K.
Highly Sensitive Detection of Minimal Cardiac Ischemia using Positron Emission Tomography Imaging of Activated Platelets
Sci Rep 2016, 6, 38161. DOI: 10.1038/srep38161
http://www.nature.com/articles/srep38161

Burvenich, I. J. G., Lee, F. T., Guo, N., Gan, H. K., Rigopoulos, A., Parslow, A.C., O’Keefe, G.J., Gong, S.J., Tochon-Danguy H., Rudd, S. E., Donnelly, P. S., Kotsuma, M., Ohtsuka, T., Senaldi, G., Scott, A.M.
In Vitro and In Vivo Evaluation of ⁸⁹Zr-DS-8273a as a Theranostic for Anti-Death Receptor 5 Therapy.
Theranostics 2016; 6(12), 2225-2234. doi:10.7150/thno.16260.
http://www.thno.org/v06p2225.htm

Paterson, B. M. and Donnelly, P. S.
Macrocyclic Bifunctional Chelators and Conjugation Strategies for Copper-64 Radiopharmaceuticals
In: Rudi van Eldik and Colin D. Hubbard, editors, Advances in Inorganic Chemistry, Vol. 68, Burlington: Academic Press, 2016, p. 223-251. ISBN: 978-0-12-803526-9. DOI: 10.1016/bs.adioch.2015.09.005
http://www.sciencedirect.com./science/article/pii/S0898883815000197

2015
Alt, K., Paterson, B. M., Westein, E., Rudd, S. E., Poniger, S. S., Jagdale, S., Ardipradja, K., Connell, T. U., Krippner, G. Y., Nair, A. K. N., Wang, X., Tochon-Danguy, H. J., Donnelly*, P. S., Peter, K. and Hagemeyer, C. E.
A Versatile Approach for the Site-Specific Modification of Recombinant Antibodies Using a Combination of Enzyme-Mediated Bioconjugation and Click Chemistry
Angew. Chem., Int. Ed. 2015 54 7515. DOI: 10.1002/anie.201411507
http://onlinelibrary.wiley.com/doi/10.1002/anie.201411507/abstract

Connell, T. U., James, J. L., White, A. R. and Donnelly*, P. S.
Protein Labelling with Versatile Phosphorescent Metal Complexes for Live Cell Luminescence Imaging
Chem. Eur. J. 2015 21 14146. DOI: 10.1002/chem.201501630
http://onlinelibrary.wiley.com/doi/10.1002/chem.201501630/abstract

North, A. J., Hayne, D. J., Schieber, C., Price, K., White, A. R., Crouch, P. J., Rigopoulos, A., O’Keefe, G. J., Tochon-Danguy, H., Scott, A. M., White, J. M., Ackermann, U. and Donnelly*, P. S.
Toward Hypoxia-Selective Rhenium and Technetium Tricarbonyl Complexes
Inorg. Chem. 2015 54 9594. DOI: 10.1021/acs.inorgchem.5b01691
http://pubs.acs.org/articlesonrequest/AOR-VmKgNqYYSfrWPfJePeZX

Hickey, J. L., James, J. L., Henderson, C. A., Price, K. A., Mot, A. I., Buncic, G., Crouch, P. J., White, J. M., White, A. R., Smith, T. A. and Donnelly*, P. S.
Intracellular Distribution of Fluorescent Copper and Zinc Bis(thiosemicarbazonato) Complexes Measured with Fluorescence Lifetime Spectroscopy
Inorg. Chem. 2015 54 9556. DOI: 10.1021/acs.inorgchem.5b01599
http://pubs.acs.org/articlesonrequest/AOR-DbIrIwciyvHjUcFWhRe9

Hayne, D. J., North, A. J., Fodero-Tavoletti, M., White, J. M., Hung, L. W., Rigopoulos, A., McLean, C. A., Adlard, P. A., Ackermann, U., Tochon-Danguy, H., Villemagne, V. L., Barnham, K. J. and Donnelly*, P. S.
Rhenium and technetium complexes that bind to amyloid-β plaques
Dalton Trans. 2015 44 4933. DOI: 10.1039/c4dt02969k
http://xlink.rsc.org/?doi=C4DT02969K

Paterson, B. M., Buncic, G., McInnes, L. E., Roselt, P., Cullinane, C., Binns, D. S., Jeffery, C. M., Price, R. I., Hicks, R. J. and Donnelly*, P. S.
Bifunctional 64Cu-labelled macrobicyclic cage amine isothiocyanates for immuno-positron emission tomography
Dalton Trans. 2015 44 4901. DOI: 10.1039/c4dt02983f
http://pubs.rsc.org/en/content/articlelanding/2015/dt/c4dt02983f#!divAbstract

Dearling, J. L. J., Paterson, B. M., Akurathi, V., Betanzos-Lara, S., Treves, S. T., Voss, S. D., White, J. M., Huston, J. S., Smith, S. V., Donnelly, P. S. and Packard, A. B.
The Ionic Charge of Copper-64 Complexes Conjugated to an Engineered Antibody Affects Biodistribution
Bioconjugate Chem. 2015 26 707. DOI: 10.1021/acs.bioconjchem.5b00049
http://pubs.acs.org/doi/abs/10.1021/acs.bioconjchem.5b00049

Gourni, E., Del Pozzo, L., Kheirallah, E., Smerling, C., Waser, B., Reubi, J.-C., Paterson, B. M., Donnelly, P. S., Meyer, P. T. and Maecke, H. R.
Copper-64 Labeled Macrobicyclic Sarcophagine Coupled to a GRP Receptor Antagonist Shows Great Promise for PET Imaging of Prostate Cancer
Mol. Pharmaceutics 2015 12 2781. DOI: 10.1021/mp500671j
http://pubs.acs.org/doi/abs/10.1021/mp500671j

Cui, J., De Rose, R., Alt, K., Alcantara, S., Paterson, B. M., Liang, K., Hu, M., Richardson, J. J., Yan, Y., Jeffery, C. M., Price, R. I., Peter, K., Hagemeyer, C. E., Donnelly, P. S., Kent, S. J. and Caruso, F.
Engineering Poly(ethylene glycol) Particles for Improved Biodistribution
ACS Nano 2015 9 1571. DOI: 10.1021/nn5061578
http://pubs.acs.org/doi/abs/10.1021/nn5061578

Kerr, E., Doeven, E. H., Barbante, G. J., Hogan, C. F., Bower, D. J., Donnelly, P. S., Connell, T. U. and Francis, P. S.
Annihilation electrogenerated chemiluminescence of mixed metal chelates in solution: modulating emission colour by manipulating the energetics
Chem. Sci. 2015 6 472. DOI: 10.1039/c4sc02697g
http://pubs.rsc.org/en/Content/ArticleLanding/2015/SC/C4SC02697G#!divAbstract

Kerr, E., Doeven, E. H., Barbante, G. J., Connell, T. U., Donnelly, P. S., Wilson, D. J. D., Ashton, T. D., Pfeffer, F. M. and Francis, P. S.
Blue Electrogenerated Chemiluminescence from Water-Soluble Iridium Complexes Containing Sulfonated Phenylpyridine or Tetraethylene Glycol Derivatized Triazolylpyridine Ligands
Chem. Eur. J. 2015 21 14987. DOI: 10.1002/chem.201502037
http://onlinelibrary.wiley.com/doi/10.1002/chem.201502037/abstract

Doeven, E. H., Barbante, G. J., Harsant, A. J., Donnelly, P. S., Connell, T. U., Hogan, C. F. and Francis, P. S.
Mobile phone-based electrochemiluminescence sensing exploiting the ‘USB On-The-Go’ protocol
Sens. Actuators, B 2015 216 608. DOI: 10.1016/j.snb.2015.04.087
http://www.sciencedirect.com/science/article/pii/S0925400516304348

Djoko, K. Y., Schembri, M. A., McEwan, A. G., Goytia, M. M., Donnelly, P. S. and Shafer, W. M.
Copper(II)-Bis(Thiosemicarbazonato) Complexes as Antibacterial Agents: Insights into Their Mode of Action and Potential as Therapeutics
Antimicrob Agents Chemother 2015 59 6444.
http://aac.asm.org/content/59/10/6444.short

Johanssen, T., Suphantarida, N., Donnelly, P. S., Liu, X. M., Petrou, S., Hill, A. F. and Barnham, K. J.
PBT2 inhibits glutamate-induced excitotoxicity in neurons through metal-mediated preconditioning
Neurobiol. Dis. 2015 81 176. DOI: 10.1016/j.nbd.2015.02.008
http://www.sciencedirect.com/science/article/pii/S0969996115000285

McAllum, E. J., Roberts, B. R., Hickey, J. L., Dang, T. N., Grubman, A., Donnelly, P. S., Liddell, J. R., White, A. R. and Crouch, P. J.
ZnII(atsm) is protective in amyotrophic lateral sclerosis model mice via a copper delivery mechanism
Neurobiol. Dis. 2015 81 20. DOI: 10.1016/j.nbd.2015.02.023
http://www.sciencedirect.com/science/article/pii/S0969996115000583

Young, T., Wijekoon, C. J. K., Spyrou, B., Donnelly, P. S., Wedd, A. G. and Xiao, Z.
A Set of Robust Fluorescent Peptide Probes for Quantification of Cu(II) Binding Affinities in the Micromolar to Femtomolar Range
Metallomics 2015 567. DOI: 10.1039/c4mt00301b
http://pubs.rsc.org/en/Content/ArticleLanding/2015/MT/C4MT00301B#!divAbstract

2014

Paterson, B. M., Alt, K., Jeffery, C. M., Price, R. I., Jagdale, S., Rigby, S., Williams, C. C., Peter, K., Hagemeyer, C. E. and Donnelly*, P. S.
Enzyme-Mediated Site-Specific Bioconjugation of Metal Complexes to Proteins: Sortase-Mediated Coupling of Copper-64 to a Single-Chain Antibody
Angew. Chem., Int. Ed. 2014  53 6115. DOI: 10.1002/anie.201402613
http://onlinelibrary.wiley.com/doi/10.1002/anie.201402613/abstract

Hayne, D. J., Lim, S. C. and Donnelly*, P. S.
Metal complexes designed to bind to amyloid-β for the diagnosis and treatment of Alzheimer’s disease
Chem. Soc. Rev. 2014  43 6701. DOI: 10.1039/c4cs00026a
http://pubs.rsc.org/en/content/articlelanding/2014/cs/c4cs00026a#!divAbstract

Connell, T. U., Schieber, C., Silvestri, I. P., White, J. M., Williams, S. J. and Donnelly*, P. S.
Copper and Silver Complexes of Tris(triazole)amine and Tris(benzimidazole)amine Ligands: Evidence that Catalysis of an Azide-Alkyne Cycloaddition (“Click”) Reaction by a Silver Tris(triazole)amine Complex Arises from Copper Impurities
Inorg. Chem. 2014  53 6503. DOI: 10.1021/ic5008999
http://pubs.acs.org/doi/abs/10.1021/ic5008999

Paterson, B. M., Roselt, P., Denoyer, D., Cullinane, C., Binns, D., Noonan, W., Jeffery, C. M., Price, R. I., White, J. M., Hicks, R. J. and Donnelly*, P. S.
PET imaging of tumours with a 64Cu labeled macrobicyclic cage amine ligand tethered to Tyr3-octreotate
Dalton Trans. 2014  43 1386. DOI: 10.1039/c3dt52647j
http://pubs.rsc.org/en/content/articlelanding/2013/dt/c3dt52647j#!divAbstract

Connell, T. U., Hayne, D. J., Ackermann, U., Tochon-Danguy, H. J., White, J. M. and Donnelly*, P. S.
Rhenium and technetium tricarbonyl complexes of 1,4-Substituted pyridyl-1,2,3-triazole bidentate click ligands conjugated to a targeting RGD peptide
J. Labelled Compd. Radiopharm. 2014  57 262. DOI: 10.1002/jlcr.3169
http://onlinelibrary.wiley.com/doi/10.1002/jlcr.3169/abstract

Zavras, A., Khairallah, G. N., Connell, T. U., White, J. M., Edwards, A. J., Mulder, R. J., Donnelly*, P. S. and O’Hair, R. A. J.
Synthesis, Structural Characterization, and Gas-Phase Unimolecular Reactivity of the Silver Hydride Nanocluster [Ag3((PPh2)2CH2)3(μ3-H)](BF4)2
Inorg. Chem. 2014  53 7429. DOI: 10.1021/ic5007499
http://pubs.acs.org/doi/abs/10.1021/ic5007499

Alt, K., Paterson, B. M., Ardipradja, K., Schieber, C., Buncic, G., Lim, B., Poniger, S. S., Jakoby, B., Wang, X., O’Keefe, G. J., Tochon-Danguy, H. J., Scott, A. M., Ackermann, U., Peter, K., Donnelly*, P. S. and Hagemeyer, C. E.
Single-Chain Antibody Conjugated to a Cage Amine Chelator and Labeled with Positron-Emitting Copper-64 for Diagnostic Imaging of Activated Platelets
Mol. Pharmaceutics 2014  11 2855. DOI: 10.1021/mp500209a
http://pubs.acs.org/doi/abs/10.1021/mp500209a

Grubman, A., James, S. A., James, J., Duncan, C., Volitakis, I., Hickey, J. L., Crouch, P. J., Donnelly, P. S., Kanninen, K. M., Liddell, J. R., Cotman, S. L., de Jonge, M. D. and White, A. R.
X-ray fluorescence imaging reveals subcellular biometal disturbances in a childhood neurodegenerative disorder
Chem. Sci. 2014  5 2503. DOI: 10.1039/c4sc00316k
http://pubs.rsc.org/en/content/articlelanding/2014/sc/c4sc00316k#!divAbstract

Barbante, G. J., Doeven, E. H., Kerr, E., Connell, T. U., Donnelly, P. S., White, J. M., Lopes, T., Laird, S., Wilson, D. J. D., Barnard, P. J., Hogan, C. F. and Francis, P. S.
Understanding Electrogenerated Chemiluminescence Efficiency in Blue-Shifted Iridium(III)-Complexes: An Experimental and Theoretical Study
Chem. – Eur. J. 2014  20 3322. DOI: 10.1002/chem.201304500
http://onlinelibrary.wiley.com/doi/10.1002/chem.201304500/abstract

Bica, L., Liddell, J., R., Duncan, C., Caragounis, A., Grubman, A., Donnelly, P., S., Paterson, B., M., Volitakis, I., Cappai, R., Camakaris, J., Crouch, P., J. and White, A., R.
Neuroprotective copper bis(thiosemicarbazonato) complexes promote neurite elongation
PLoS One 2014  9 e90070.
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0090070

Djoko, K. Y., Donnelly, P. S. and McEwan, A. G.
Inhibition of respiratory Complex I by copper(II)-bis(thiosemicarbazonato) complexes
Metallomics 2014  6 2250. DOI: 10.1039/c4mt00226a
http://pubs.rsc.org/en/Content/ArticleLanding/2014/MT/c4mt00226a#!divAbstract

Djoko, K. Y., Paterson, B. M., Donnelly, P. S. and McEwan, A. G.
Antimicrobial effects of copper(II) bis(thiosemicarbazonato) complexes provide new insight into their biochemical mode of action
Metallomics 2014  6 854. DOI: 10.1039/c3mt00348e
http://pubs.rsc.org/en/Content/ArticleLanding/2014/MT/c3mt00348e#!divAbstract

Grubman, A., Lidgerwood, G. E., Duncan, C., Bica, L., Tan, J.-L., Parker, S. J., Caragounis, A., Meyerowitz, J., Volitakis, I., Moujalled, D., Liddell, J. R., L., H. J., Horne, M., Longmuir, S., Koistinaho, J., Donnelly, P. S., Crouch, P. J., Tammen, I., White, A. R. and Kanninen, K. M.
Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder
Acta Neuropathol Commun 2014  2 25.
http://actaneurocomms.biomedcentral.com/articles/10.1186/2051-5960-2-25

Noor, A., Huff, G. S., Kumar, S. V., Lewis, J. E. M., Paterson, B. M., Schieber, C., Donnelly, P. S., Brooks, H. J. L., Gordon, K. C., Moratti, S. C. and Crowley, J. D.
[Re(CO)3]+ Complexes of exo-Functionalized Tridentate “Click” Macrocycles: Synthesis, Stability, Photophysical Properties, Bioconjugation, and Antibacterial Activity
Organometallics 2014  33 7031.
http://pubs.acs.org/doi/abs/10.1021/om500664v

Roberts, B. R., Turner, B. J., Bush, A. I., Masters, C. L., Li, Q.-X., Lim Nastasia, K. H., McAllum, E. J., Price, K. A., Kanninen, K. M., Liddell, J. R., Grubman, A., Donnelly, P. S., Lim, S., Paterson, B. M., Hickey, J. L., Hare, D. J., Doble, P. A., Rhoads, T. W., Williams, J. R., Hung Lin, W., Monty, J.-F., Llanos, R. M., Mercer, J. F. B., Kramer, D. R., Duce, J. A., Beckman, J. S., Barnham, K. J., White, A. R. and Crouch, P. J.
Oral Treatment with CuII(atsm) Increases Mutant SOD1 In Vivo but Protects Motor Neurons and Improves the Phenotype of a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis
J Neurosci 2014  34 8021.
http://www.jneurosci.org/content/34/23/8021.abstract

Woolley, M., Ariafard, A., Khairallah, G. N., Kwan, K. H.-Y., Donnelly, P. S., White, J. M., Canty, A. J., Yates, B. F. and O’Hair, R. A. J.
Decarboxylative-Coupling of Allyl Acetate Catalyzed by Group 10 Organometallics, [(phen)M(CH3)]+
J. Org. Chem. 2014  79 12056. DOI: 10.1021/jo501886w
http://pubs.acs.org/doi/abs/10.1021/jo501886w

Woolley, M., Khairallah, G. N., da Silva, G., Donnelly, P. S. and O’Hair, R. A. J.
Direct versus Water-Mediated Protodecarboxylation of Acetic Acid Catalyzed by Group 10 Carboxylates, [(phen)M(O2CCH3)]+
Organometallics 2014  33 5185. DOI: 10.1021/om500493w
http://pubs.acs.org/doi/abs/10.1021/om500493w

 

2013

Hickey, J. L., Lim, S. C., Hayne, D. J., Paterson, B. M., White, J. M., Villemagne, V. L., Roselt, P., Binns, D., Cullinane, C., Jeffery, C. M., Price, R. I., Barnham, K. J. and Donnelly*, P. S.
Diagnostic Imaging Agents for Alzheimer’s Disease: Copper Radiopharmaceuticals that Target AŒ≤ Plaques
J. Am. Chem. Soc. 2013  135 16120. DOI: 10.1021/ja4057807
http://pubs.acs.org/doi/abs/10.1021/ja4057807

Zavras, A., Khairallah, G. N., Connell, T. U., White, J. M., Edwards, A. J., Donnelly*, P. S. and O’Hair, R. A. J.
Synthesis, Structure and Gas-Phase Reactivity of a Silver Hydride Complex [Ag3{(PPh2)2CH2}3(μ3-H)(μ3-Cl)]BF4
Angew. Chem., Int. Ed. 2013  52 8391. DOI: 10.1002/anie.201302436
http://onlinelibrary.wiley.com/doi/10.1002/anie.201302436/abstract

van der Peet, P. L., Connell, T. U., Gunawan, C., White, J. M., Donnelly*, P. S. and Williams, S. J.
A Click Chemistry Approach to 5,5′-Disubstituted-3,3′-Bisisoxazoles from Dichloroglyoxime and Alkynes: Luminescent Organometallic Iridium and Rhenium Bisisoxazole Complexes
J. Org. Chem. 2013  78 7298. DOI: 10.1021/jo4008755
http://pubs.acs.org/doi/abs/10.1021/jo4008755

Cater, M. A., Pearson, H. B., Wolyniec, K., Klaver, P., Bilandzic, M., Paterson, B. M., Bush, A. I., Humbert, P. O., La Fontaine, S., Donnelly, P. S. and Haupt, Y.
Increasing Intracellular Bioavailable Copper Selectively Targets Prostate Cancer Cells
ACS Chem. Biol. 2013  8 1621. DOI: 10.1021/cb400198p
http://pubs.acs.org/doi/abs/10.1021/cb400198p

Connell, T. U., Sandanayake, S., Khairallah, G. N., White, J. M., O’Hair, R. A. J., Donnelly*, P. S. and Williams, S. J.
Halide-ion-templated Ag8Cu6 rhombic dodecahedrons: synthesis, structure and reactivity of [Ag8Cu6(C≡CtBu)12X]BF4 (X = Cl, Br)
Dalton Trans. 2013  42 4903. DOI: 10.1039/c3dt33027c
http://pubs.rsc.org/en/Content/ArticleLanding/2013/DT/C3DT33027C#!divAbstract

Duncan, C., Bica, L., Crouch, P. J., Caragounis, A., Lidgerwood, G. E., Parker, S. J., Meyerowitz, J., Volitakis, I., Liddell, J. R., Raghupathi, R., Paterson, B. M., Duffield, M. D., Cappai, R., Donnelly, P. S., Grubman, A., Camakaris, J., Keating, D. J. and White, A. R.
Copper modulates the large dense core vesicle secretory pathway in PC12 cells
Metallomics 2013  5 700. DOI: 10.1039/c3mt20231c
http://pubs.rsc.org/en/Content/ArticleLanding/2013/MT/c3mt20231c#!divAbstract

Kanninen, K. M., Grubman, A., Meyerowitz, J., Duncan, C., Tan, J.-L., Parker, S. J., Crouch, P. J., Paterson, B. M., Hickey, J. L., Donnelly, P. S., Volitakis, I., Tammen, I., Palmer, D. N. and White, A. R.
Increased zinc and manganese in parallel with neurodegeneration, synaptic protein changes and activation of Akt/GSK3 signaling in ovine CLN6 neuronal ceroid lipofuscinosis
PLoS One 2013  8 e58644. DOI: 10.1371/journal.pone.0058644
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0058644

McAllum, E. J., Lim, N. K. H., Hickey, J. L., Paterson, B. M., Donnelly, P. S., Li, Q.-X., Liddell, J. R., Barnham, K. J., White, A. R. and Crouch, P. J.
Therapeutic effects of CuII(atsm) in the SOD1-G37R mouse model of amyotrophic lateral sclerosis
Amyotrophic Lateral Scler. Frontotemporal Degener. 2013  14 586. DOI: 10.3109/21678421.2013.824000
http://www.tandfonline.com/doi/abs/10.3109/21678421.2013.824000?journalCode=iafd20

Sze, C. M., Shi, Z., Khairallah, G. N., Feketeova, L., O’Hair, R. A. J., Xiao, Z., Donnelly, P. S. and Wedd, A. G.
Interaction of cisplatin and analogue Pt(en)Cl2 with the copper metallo-chaperone Atox1
Metallomics 2013  5 946. DOI: 10.1039/c3mt00082f
http://pubs.rsc.org/en/Content/ArticleLanding/2013/MT/c3mt00082f#!divAbstract

Woolley, M. J., Khairallah, G. N., da Silva, G., Donnelly, P. S., Yates, B. F. and O’Hair, R. A. J.
Role of the Metal, Ligand, and Alkyl/Aryl Group in the Hydrolysis Reactions of Group 10 Organometallic Cations [(L)M(R)]+
Organometallics 2013  32 6931. DOI: 10.1021/om400358q
http://pubs.acs.org/doi/abs/10.1021/om400358q

 

 

2012

Conjugation of Transferrin to Azide-Modified CdSe/ZnS Core–Shell Quantum Dots using Cyclooctyne Click Chemistry, C. Schieber,* A. Bestetti, J. P. Lim, A. D. Ryan, T. Nguyen, R. Eldridge, A. R. White, P. A. Gleeson, P. S. Donnelly,* S. J. Williams,* and P. Mulvaney*, Angew. Chem. Int. Ed. 2012, 51, 10523 –10527
http://onlinelibrary.wiley.com/doi/10.1002/anie.201202876/full

The challenges of using a copper fluorescent sensor (CS1) to track intracellular distributions of copper in neuronal and glial cells, Price, K. A.; Hickey, J. L.; Xiao, Z.; Wedd, A. G.; James, S. A.; Liddell, J. R.; Crouch, P. J.; White, A. R.; Donnelly*, P. S.Chem. Sci., 2012, 3, 2748-2759.
http://pubs.rsc.org/en/Content/ArticleLanding/2012/SC/c2sc20397a#!divAbstract

An impaired mitochondrial electron transport chain increases retention of the hypoxia imaging agent diacetylbis(4-methylthiosemicarbazonato)copperII, Donnelly, P. S.; Liddell, J. R.; Lim, S.; Paterson, B. M.; Cater, M. A.; Savva, M. S.; Mo, A. I.; James, J. L.; Trounce, I. A.; White, A. R.; Crouch, P. J.Proc. Natl. Acad. Sci. (USA), 2012, 109, 47-52.
http://www.pnas.org/content/109/1/47.full.pdf

Copper complexes of a novel non-innocent quadridentate ligand, Buncic, G.; Xiao, Z.; Drew, S. C.; White, J. M.; Wedd, A. G.; Donnelly*, P. S.Chem. Commun., 2012, 48, 2570-2572.
http://pubs.rsc.org/en/content/articlelanding/2012/cc/c2cc16658e#!divAbstract

Diagnostic imaging of Alzheimer’s disease with copper and technetium complexes, Hickey, J. L.; Donnelly*, P. S.Coord. Chem. Rev., 2012, 256, 2367-2380.
http://www.sciencedirect.com/science/article/pii/S0010854512000793

Comparison of 64Cu-Complexing Bifunctional Chelators for Radioimmunoconjugation: Labeling Efficiency, Specific Activity, and in Vitro/in Vivo Stability, Cooper, M. S.; Ma, M. T.; Sunassee, K.; Shaw, K. P.; Williams, J. D.; Paul, R. L.; Donnelly, P. S.; Blower, P. J.Bioconjug. Chem., 2012, 23, 1029-1039.
http://pubs.acs.org/doi/abs/10.1021/bc300037w

Inhibition of TDP-43 accumulation by Bis(thiosemicarbazonato)-copper complexes, Parker, S. J.; Meyerowitz, J.; James, J. L.; Liddell, J. R.; Nonaka, T.; Hasegawa, M.; Kanninen, K. M.; Lim, S. C.; Paterson, B. M.; Donnelly, P. S.; Crouch, P. J.; White, A. R.PLoS One, 2012, 7, e42277.
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0042277

The hypoxia imaging agent CuII(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson’s disease, Hung, L. W.; Villemagne, V. L.; Cheng, L.; Sherratt, N. A.; Ayton, S.; White, A. R.; Crouch, P. J.; Lim, S.; Leong, S. L.; Wilkins, S.; George, J.; Roberts, B. R.; Pham, C. L. L.; Liu, X.; Chiu, F. C. K.; Shackleford, D. M.; Powell, A. K.; Masters, C. L.; Bush, A. I.; O’Keefe, G.; Culvenor, J. G.; Cappai, R.; Cherny, R. A.; Donnelly, P. S.; Hill, A. F.; Finkelstein, D. I.; Barnham, K. J.J. Exp. Med., 2012, 209, 837-854.
http://jem.rupress.org/content/209/4/837.full.pdf+html

 

2011

Nitrogen adduction by three coordinate group 10 organometallic cations: platinum is favoured over nickel and palladium, Woolley, M. J.; Khairallah, G. N.; Donnelly, P. S.; O’Hair, R. A. J.Rapid Commun. Mass Spectrom., 2011, 25, 2083-2088.

Diacetylbis(N(4)-methylthiosemicarbazonato) Copper(II) (CuII(atsm)) Protects against Peroxynitrite-induced Nitrosative Damage and Prolongs Survival in Amyotrophic Lateral Sclerosis Mouse Model, Soon, C. P. W.; Donnelly, P. S.; Turner, B. J.; Hung, L. W.; Crouch, P. J.; Sherratt, N. A.; Tan, J.-L.; Lim, N. K. H.; Lam, L.; Bica, L.; Lim, S.; Hickey, J. L.; Morizzi, J.; Powell, A.; Finkelstein, D. I.; Culvenor, J. G.; Masters, C. L.; Duce, J.; White, A. R.; Barnham, K. J.; Li, Q.-X.J. Biol. Chem., 2011, 286, 44035-44044.

Cellular Up-Regulation of Nedd4 Family Interacting Protein 1 (Ndfip1) using Low Levels of Bioactive Cobalt Complexes, Schieber, C.; Howitt, J.; Putz, U.; White, J. M.; Parish, C. L.; Donnelly, P. S.; Tan, S.-S.J. Biol. Chem., 2011, 286, 8555-8564.

Copper(I)-catalyzed cycloaddition of silver acetylides and azides: Incorporation of volatile acetylenes into the triazole core, Proietti Silvestri, I.; Andemarian, F.; Khairallah, G. N.; Wan Yap, S.; Quach, T.; Tsegay, S.; Williams, C. M.; O’Hair, R. A. J.; Donnelly, P. S.; Williams, S. J.Org. Biomol. Chem., 2011, 9, 6082-6088.

Mechanisms Controlling the Cellular Accumulation of Copper Bis(thiosemicarbazonato) Complexes, Price, K. A.; Crouch, P. J.; Volitakis, I.; Paterson, B. M.; Lim, S.; Donnelly, P. S.; White, A. R.Inorg. Chem., 2011, 50, 9594-9605.

Subcellular localization of a fluorescent derivative of CuII(atsm) offers insight into the neuroprotective action of CuII(atsm), Price, K. A.; Crouch, P. J.; Lim, S.; Paterson, B. M.; Liddell, J. R.; Donnelly, P. S.; White, A. R.Metallomics, 2011, 3, 1280-1290.

Copper complexes of bis(thiosemicarbazones): from chemotherapeutics to diagnostic and therapeutic radiopharmaceuticals, Paterson, B. M.; Donnelly, P. S.Chem. Soc. Rev., 2011, 40, 3005-3018.

Gallium-68 Complex of a Macrobicyclic Cage Amine Chelator Tethered to Two Integrin-Targeting Peptides for Diagnostic Tumor Imaging, Ma, M. T.; Neels, O. C.; Denoyer, D.; Roselt, P.; Karas, J. A.; Scanlon, D. B.; White, J. M.; Hicks, R. J.; Donnelly, P. S.Bioconjug. Chem., 2011, 22, 2093-2103.

Peptide targeted copper-64 radiopharmaceuticals, Ma, M. T.; Donnelly, P. S.Current Topics in Medicinal Chemistry 2011, 11, 500-520.

Macrobicyclic Cage Amine Ligands for Copper Radiopharmaceuticals: A Single Bivalent Cage Amine Containing Two Lys3-bombesin Targeting Peptides, Ma, M. T.; Cooper, M. S.; Paul, R. L.; Shaw, K. P.; Karas, J. A.; Scanlon, D.; White, J. M.; Blower, P. J.; Donnelly, P. S.Inorg. Chem., 2011, 50, 6701-6710.

Copper(II) complexes of hybrid hydroxyquinoline-thiosemicarbazone ligands: GSK3β inhibition due to intracellular delivery of copper, Hickey, J. L.; Crouch, P. J.; Mey, S.; Caragounis, A.; White, J. M.; White, A. R.; Donnelly, P. S.Dalton Trans., 2011, 40, 1338-1347.

The role of coordination chemistry in the development of copper and rhenium radiopharmaceuticals, Donnelly, P. S.Dalton Trans., 2011, 40, 999-1010.

The Alzheimer’s therapeutic PBT2 promotes amyloid-Œ≤ degradation and GSK3 phosphorylation via a metal chaperone activity, Crouch Peter, J.; Savva Maria, S.; Hung Lin, W.; Donnelly Paul, S.; Mot Alexandra, I.; Parker Sarah, J.; Greenough Mark, A.; Volitakis, I.; Adlard Paul, A.; Cherny Robert, A.; Masters Colin, L.; Bush Ashley, I.; Barnham Kevin, J.; White Anthony, R.J Neurochem, 2011, 119, 220-30.

Water-soluble Bis(thiosemicarbazonato)copper(II) Complexes, Buncic, G.; Hickey, J. L.; Schieber, C.; White, J. M.; Crouch, P. J.; White, A. R.; Xiao, Z.; Wedd, A. G.; Donnelly, P. S.Aust. J. Chem., 2011, 64, 244-252.

Cell cycle arrest in cultured neuroblastoma cells exposed to a bis(thiosemicarbazonato) metal complex, Bica, L.; Meyerowitz, J.; Parker, S. J.; Caragounis, A.; Du, T.; Paterson, B. M.; Barnham, K. J.; Crouch, P. J.; White, A. R.; Donnelly, P. S.BioMetals, 2011, 24, 117-133.

Metal ionophore treatment restores dendritic spine density and synaptic protein levels in a mouse model of Alzheimer’s disease, Adlard, P. A.; Bica, L.; White, A. R.; Nurjono, M.; Filiz, G.; Crouch, P. J.; Donnelly, P. S.; Cappai, R.; Finkelstein, D. I.; Bush, A. I.PLoS One, 2011, 6, e17669.

 

2010

A hexadentate bis(thiosemicarbazonato) ligand: rhenium(v), iron(iii) and cobalt(iii) complexes, Paterson, B. M.; White, J. M.; Donnelly, P. S.Dalton Trans., 2010, 39, 2831-2837.

Versatile New Bis(thiosemicarbazone) Bifunctional Chelators: Synthesis, Conjugation to Bombesin(7-14)-NH2, and Copper-64 Radiolabeling, Paterson, B. M.; Karas, J. A.; Scanlon, D. B.; White, J. M.; Donnelly, P. S.Inorg. Chem., 2010, 49, 1884-1893.

Copper and zinc bis(thiosemicarbazonato) complexes with a fluorescent tag: synthesis, radiolabelling with copper-64, cell uptake and fluorescence studies, Lim, S.; Price, K. A.; Chong, S.-F.; Paterson, B. M.; Caragounis, A.; Barnham, K. J.; Crouch, P. J.; Peach, J. M.; Dilworth, J. R.; White, A. R.; Donnelly, P. S.J. Biol. Inorg. Chem., 2010, 15, 225-235.

A copper radiopharmaceutical for diagnostic imaging of Alzheimer’s disease: a bis(thiosemicarbazonato)copper(ii) complex that binds to amyloid-Œ≤ plaques, Lim, S.; Paterson, B. M.; Fodero-Tavoletti, M. T.; O’Keefe, G. J.; Cappai, R.; Barnham, K. J.; Villemagne, V. L.; Donnelly, P. S.Chem. Commun., 2010, 46, 5437-5439.

Bis(thiosemicarbazonato) Cu-64 Complexes for Positron Emission Tomography Imaging of Alzheimer’s Disease, Fodero-Tavoletti, M. T.; Villemagnea, V. L.; Paterson, B. M.; White, A. R.; Li, Q.-X.; Camakaris, J.; O’Keefe, G.; Cappai, R.; Barnham, K. J.; Donnelly, P. S.J. Alz. Dis., 2010, 20, 49-55.

A Water-Soluble Bis(thiosemicarbazone) Ligand. A Sensitive Probe and Metal Buffer for Zinc, Buncic, G.; Donnelly, P. S.; Paterson, B. M.; White, J. M.; Zimmermann, M.; Xiao, Z.; Wedd, A. G.Inorg. Chem., 2010, 49, 3071-3073.

 

2009

Interaction of cisplatin and analogues with a Met-rich protein site, Sze, C. M.; Khairallah, G. N.; Xiao, Z.; Donnelly, P. S.; O’Hair, R. A. J.; Wedd, A. G.J. Biol. Inorg. Chem., 2009, 14, 163-165.

Membrane-targeted strategies for modulating APP and Abeta -mediated toxicity, Price, K. A.; Crouch, P. J.; Donnelly, P. S.; Masters, C. L.; White, A. R.; Curtain, C. C.J. Cell. Mol. Med., 2009, 13, 249-261.

Sustained Activation of Glial Cell Epidermal Growth Factor Receptor by Bis(thiosemicarbazonato) Metal Complexes is Associated with Inhibition of Protein Tyrosine Phosphatase Activity, Price, K. A.; Caragounis, A.; Paterson, B. M.; Filiz, G.; Volitakis, I.; Masters, C. L.; Barnham, K. J.; Donnelly, P. S.; Crouch, P. J.; White, A. R.J. Med. Chem., 2009, 52, 6606-6620.

A new bifunctional chelator for copper radiopharmaceuticals: A cage amine ligand with a carboxylate functional group for conjugation to peptides, Ma, M. T.; Karas, J. A.; White, J. M.; Scanlon, D.; Donnelly, P. S.Chem. Commun., 2009, 3237-3239.

Increasing Cu bioavailability inhibits Abeta oligomers and tau phosphorylation, Crouch, P. J.; Hung, L. W.; Adlard, P. A.; Cortes, M.; Lal, V.; Filiz, G.; Perez, K. A.; Nurjono, M.; Caragounis, A.; Du, T.; Laughton, K.; Volitakis, I.; Bush, A. I.; Li, Q.-X.; Masters, C. L.; Cappai, R.; Cherny, R. A.; Donnelly, P. S.; White, A. R.; Barnham, K. J.Proc. Natl. Acad. Sci. U. S. A., 2009, 106, 381-386.

Variations on a Cage Theme: Some Complexes of Bicyclic Polyamines as Supramolecular Synthons, Clark, I. J.; Crispini, A.; Donnelly, P. S.; Engelhardt, L. M.; Harrowfield, J. M.; Jeong, S.-H.; Kim, Y.; Koutsantonis, G. A.; Lee, Y. H.; Lengkeek, N. A.; Mocerino, M.; Nealon, G. L.; Ogden, M. I.; Park, Y. C.; Pettinari, C.; Polanzan, L.; Rukmini, E.; Sargeson, A. M.; Skelton, B. W.; Sobolev, A. N.; Thuery, P.; White, A. H.Aust. J. Chem., 2009, 62, 1246-1260.

 

2008

Transfer of Copper between Bis(thiosemicarbazone) Ligands and Intracellular Copper-Binding Proteins. Insights into Mechanisms of Copper Uptake and Hypoxia Selectivity, Xiao, Z.; Donnelly, P. S.; Zimmermann, M.; Wedd, A. G.Inorg. Chem., 2008, 47, 4338-4347

Activation of epidermal growth factor receptor by metal-ligand complexes decreases levels of extracellular amyloid beta peptide, Price, K. A.; Filiz, G.; Caragounis, A.; Du, T.; Laughton, K. M.; Masters, C. L.; Sharples, R. A.; Hill, A. F.; Li, Q.-X.; Donnelly, P. S.; Barnham, K. J.; Crouch, P. J.; White, A. R.Int. J. Biochem. Cell Biol., 2008, 40, 1901-1917.

‘Click’ cycloaddition catalysts: copper(i) and copper(ii) tris(triazolylmethyl)amine complexes, Donnelly, P. S.; Zanatta, S. D.; Zammit, S. C.; White, J. M.; Williams, S. J.Chem. Commun., 2008, 2459-2461.

Selective Intracellular Release of Copper and Zinc Ions from Bis(thiosemicarbazonato) Complexes Reduces Levels of Alzheimer Disease Amyloid-beta Peptide, Donnelly, P. S.; Caragounis, A.; Du, T.; Laughton, K. M.; Volitakis, I.; Cherny, R. A.; Sharples, R. A.; Hill, A. F.; Li, Q.-X.; Masters, C. L.; Barnham, K. J.; White, A. R.J. Biol. Chem., 2008, 283, 4568-4577.

 

2007

Functionalized Bis(thiosemicarbazonato) Complexes of Zinc and Copper: Synthetic Platforms Toward Site-Specific Radiopharmaceuticals, Holland, J. P.; Aigbirhio, F. I.; Betts, H. M.; Bonnitcha, P. D.; Burke, P.; Christlieb, M.; Churchill, G. C.; Cowley, A. R.; Dilworth, J. R.; Donnelly, P. S.; Green, J. C.; Peach, J. M.; Vasudevan, S. R.; Warren, J. E.Inorg. Chem.,2007, 46, 465-485.

Copper and Alzheimer’s disease, Donnelly, P. S.; Xiao, Z.; Wedd, A. G.Curr. Opin. Chem. Biol., 2007, 11, 128-133

Alzheimer’s disease and the chemistry of copper, Donnelly, P. S.; Wedd, A. G.Chemistry in Australia, 2007, 74, 18-20.

Copper and zinc bis(thiosemicarbazonato) complexes for the treatment of Alzheimer’s disease, Donnelly, P. S.; Barnham, K. J.; White, A. R.J. Biol. Inorg. Chem., 2007, 12, S17.

Dilworth, J. R.; Peach, J. M.; Heslop, J. M.; Donnelly, P. S.; (Isis Innovation Limited, UK). Application: WO

WO, 2007; pp 132pp.

Rhenium diazenide ternary complexes with dithiocarbamate ligands: Towards new rhenium radiopharmaceuticals, Cowley, A. R.; Dilworth, J. R.; Donnelly, P. S.; Ross, S. J.Dalton Trans., 2007, 73-82.

Bifunctional chelators for copper radiopharmaceuticals: the synthesis of [Cu(ATSM)-amino acid] and [Cu(ATSM)-octreotide] conjugates, Cowley, A. R.; Dilworth, J. R.; Donnelly, P. S.; Heslop, J. M.; Ratcliffe, S. J.Dalton Trans., 2007, 209-217.

New bimetallic compounds based on the bis(thiosemicarbazonato) motif, Christlieb, M.; Cowley, A. R.; Dilworth, J. R.; Donnelly, P. S.; Paterson, B. M.; Struthers, H. S. R.; White, J. M.Dalton Trans., 2007, 327-331.

 

2006

Copper Complexes of Thiosemicarbazone-Pyridylhydrazine (THYNIC) Hybrid Ligands: A New Versatile Potential Bifunctional Chelator for Copper Radiopharmaceuticals, Cowley, A. R.; Dilworth, J. R.; Donnelly, P. S.; White, J. M.Inorg. Chem., 2006, 45, 496-498.

 

2005

Radiosynthesis of novel copper(II) bis(thiosemicarbazone) PET tracers, Donnelly, P. S.; Golovko, O.; Heslop, J. M.; Burke, P.; Clark, J. C.; Dilworth, J. R.; Aigbirhio, F. I.J. Label. Compd. Radiopharm., 2005, 48, S163.

Therapeutic Rhenium Radiopharmaceuticals – In Metallotherapeutics – The Use of Metal-Based Drugs in Medicine, Dilworth, J. R.; Donnelly, P. S.Therapeutic Rhenium Radiopharmaceuticals – In Metallotherapeutics – The Use of Metal-Based Drugs in Medicine, 2005, 463-487.

Fluorescence studies of the intra-cellular distribution of zinc bis(thiosemicarbazone) complexes in human cancer cells, Cowley, A. R.; Davis, J.; Dilworth, J. R.; Donnelly, P. S.; Dobson, R.; Nightingale, A.; Peach, J. M.; Shore, B.; Kerr, D.; Seymour, L.Chem. Commun., 2005, 845-847.

Investigations into some aryl substituted bis(thiosemicarbazones) and their copper complexes, Alsop, L.; Cowley, A. R.; Dilworth, J. R.; Donnelly, P. S.; Peach, J. M.; Rider, J. T.Inorg. Chim. Acta, 2005, 358, 2770-2780.

 

2004

Acetylacetonate bis(thiosemicarbazone) complexes of copper and nickel: towards new copper radiopharmaceuticals, Cowley, A. R.; Dilworth, J. R.; Donnelly, P. S.; Gee, A. D.; Heslop, J. M.Dalton Trans., 2004, 2404-2412.

Pyridylthiocarbazide complexes of rhenium with potential radiopharmaceutical applications, Clarke, C.; Cowley, A. R.; Dilworth, J. R.; Donnelly, P. S.Dalton Trans., 2004, 2402-2403.

Functionalized Thiosemicarbazone Clusters of Copper(I) and Silver(I), Ashfield, L. J.; Cowley, A. R.; Dilworth, J. R.; Donnelly, P. S.Inorg. Chem., 2004, 43, 4121-4123.

Diazenide and hydrazide(2-) derivatives of the [Re(CO)3]+ core, Alberto, R.; Cowley, A. R.; Dilworth, J. R.; Donnelly, P. S.; Pratt, J.Dalton Trans., 2004, 2610-2611.

 

2003

Neutral molecule complex-structural characterization of some adducts of urea and thiourea with N,N’-bidentate aromatic bases, Donnelly, P. S.; Skelton, B. W.; White, A. H.Aust. J. Chem., 2003, 56, 1249-1253.

Synthesis and characterisation of new homoleptic rhenium thiosemicarbazone complexes, Cowley, A. R.; Dilworth, J. R.; Donnelly, P. S.; Woollard-Shore, J.Dalton Trans., 2003, 748-754.

A Mono-Diazenide Complex from Perrhenate: Toward a New Core for Rhenium Radiopharmaceuticals, Cowley, A. R.; Dilworth, J. R.; Donnelly, P. S.Inorg. Chem., 2003, 42, 929-931.

Structural trends in copper(II) bis(thiosemicarbazone) radiopharmaceuticals, Blower, P. J.; Castle, T. C.; Cowley, A. R.; Dilworth, J. R.; Donnelly, P. S.; Labisbal, E.; Sowrey, F. E.; Teat, S. J.; Went, M. J.Dalton Trans., 2003, 4416-4425.

 

2002

Synthesis with coordinated ligands: biomolecule attachment to cage amines, Donnelly, P. S.; Harrowfield, J. M.J. Chem. Soc., Dalton Trans., 2002, 906-913.

Towards New Copper and Rhenium Based Radiopharmaceuticals – In Technetium, Rhenium and Other Metals in Chemistry and Nuclear Medicine 6, Eds., M. Nicolini, and U. Mazzi, SGE Ditoriali, Padova, 2002, p. 223, Cowley, A. R.; Dilworth, J. R.; Donnelly, P. S.; Ross, S. J..

An Unusual Dimeric Structure of a Cu(I) Bis(thiosemicarbazone) Complex: Implications for the Mechanism of Hypoxic Selectivity of the Cu(II) Derivatives, Cowley, A. R.; Dilworth, J. R.; Donnelly, P. S.; Labisbal, E.; Sousa, A.J. Am. Chem. Soc., 2002, 124, 5270-5271.

Towards New Copper and Rhenium Based Radiopharmaceuticals – In Technetium, Rhenium and Other Metals in Chemistry and Nuclear Medicine 6, Eds., M. Nicolini, and U. Mazzi, SGE Ditoriali, Padova, 2002, p. 91, Ashfield, L. J.; Clarke, C.; Cowley, A. R.; Dilworth, J. R.; Donnelly, P. S.; Heslop, J. M.

 

2001

An octapositive cation incorporating multiple redox centres: cage amine complexes of cobalt(III) linked by a 2,2′-bis(pyridinium) unit, Donnelly, P. S.; Harrowfield, J. M.; Skelton, B. W.; White, A. H.Aust. J. Chem., 2001, 54, 15-17.

Carboxymethylated Cage Amines: Coordination and Lactamization, Donnelly, P. S.; Harrowfield, J. M.; Skelton, B. W.; White, A. H.Inorg. Chem., 2001, 40, 5645-5652.

Chirality in coordination polymers: homo- vs. hetero-chiral strand construction, Donnelly, P. S.; Harrowfield, J. M.; Skelton, B. W.; White, A. H.J. Chem. Soc., Dalton Trans., 2001, 3078-3083.

Functionalization of cage amines with pendant aromatic and heteroaromatic substituents, Burnet, S.; Choi, M.-H.; Donnelly, P. S.; Harrowfield, J. M.; Ivanova, I.; Jeong, S.-H.; Kim, Y.; Mocerino, M.; Skelton, B. W.; White, A. H.; Williams, C. C.; Zeng, Z.-L.Eur. J. Inorg. Chem., 2001, 1869-1881.

 

2000

Carboxymethylation of Cage Amines: Control of Alkylation by Metal Ion Coordination, Donnelly, P. S.; Harrowfield, J. M.; Skelton, B. W.; White, A. H.Inorg. Chem., 2000, 39, 5817-5830.